Drone can refer to:
- Combat Drone - enemy in Serious Sam 4 and Serious Sam: Siberian Mayhem.
- Drone (SSVR:TLH) - enemy in Serious Sam VR: The Last Hope.
- Drone Squad - power up in Serious Sam VR: The Last Hope.
- Hacked Drone - gadget in Serious Sam 4 and Serious Sam: Siberian Mayhem.
- Harvester Drone - enemy in Serious Sam 4.
- Propaganda Drone - enemy in Serious Sam 4.
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